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Charlie could refer to:

• "Charlie", a nickname for the Vietnamese during the Vietnam War.
• Charlie Andrews, the waitress from the Burnt Toast Diner who was killed by Sylar.
• Charlottesville, VA, the location of the University of Virginia.
• Charles Darwin, whose work is often referred to in Heroes.
• Charles Deveaux, Simone's father who was cared for by Peter Petrelli.
• Chuck Kim, a writer for Heroes and its graphic novels.
• Charlie Lieberman, a director of photography for Heroes.
• Saving Charlie, the book that details Hiro's mission to save Charlie from dying.
• Charlie Svenson, the young tech tycoon and Drucker historian featured in the Global News Interactive videos posted on Hana's website.