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Cain could refer to:
- Ben Cain, the actor who portrays a museum guard.
- Cainan, GA, the city where the Greers' home is located.
- Cain Hobson, Arthur's golfing buddy, according to a deleted scene from It's Coming, as seen on the Season Three DVD.
- Kanin Howell, the actor who portrays Gael Cruz.
- "Kane", the name by which Adam Monroe was originally going to have, according to early spoilers.
- Adam Kane, a director for Heroes.
- Eden McCain, an evolved human with the power of persuasion.